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KMID : 0438520120190010017
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Journal of the Korean Society of Neonatology
2012 Volume.19 No. 1 p.17 ~ p.25
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Outpatient Follow-up Status and Neurodevelopmental Outcomes of Extremely Low Birth Weight Infants
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Kim Su-Yeong
Song In-gu
Kim Cu-Rie
Kim Yoon-Joo
Shin Seung-Han
Lee Seung-Hyun
Lee Jae-Myoung
Lee Ju-Young
Sohn Jin-A
Lee Hyun-Ju
Lee Jin-A
Choi Chang-Won
Kim Ee-Kyung
Kim Han-Suk
Kim Beyong-Il
Choi Jung-Hwan
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Abstract
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Purpose: To report the follow-up status and neurodevelopmental outcomes of extremely low birth weight (ELBW) survivors at 18 months’ corrected age (CA).
Method: We performed a retrospective study of 130 ELBW infants admitted to neonatal intensive care unit of Seoul National University Children’s Hospital between January 2005 and May 2009. The follow-up status and neurodevelopmental outcomes were evaluated until the CA of 18 months. The assessment of outcomes included cerebral palsy, cognitive developmental delay, blindness, deafness and catch-up growth. Clinical data were collected to identify the factors influencing neurodevelopmental disability.
Results: Of the 130 survivors at discharge, 122 (93.8%) participated in the follow-up at 18 months’ CA. Study characteristics included a mean birth weight of 783 g and a mean gestation of 27 weeks. One hundred and eleven infants (85.4%) were evaluated for cerebral palsy (CP) and 11 (9.9%) were identified with CP. Eighty five infants (74.6%) were assessed with the Bayley Scales of Infant Development-III (BSID-III) at 8 months’ CA and 2 (2.4%) had a cognitive scale <70. Fifty four infants (41.9%) were assessed with BSID-III at 18 months’ CA and 2 (3.7%) had a cognitive scale <70. There were 2 (1.2%) cases of blindness and the case of deafness was not present in this study. The failure of catch-up growth was seen in 40 (32.8%) infants. Severe intraventricular hemorrhage, periventricular leukomalacia, hydrocephalus and shunt insertion were the most important risk factors for neurologic abnormality.
Conclusion: In our institution, neurodevelopmental outcomes of ELBW survivors were comparable to recent reports from the USA. ELBW infants need to be monitored on multidisciplinary follow-up programs and more efforts should be made to improve the follow-up.
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KEYWORD
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Outcome assessment, Growth & development, Infant, Extremely low birth weight
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